SARS-CoV-2 envelope protein triggers depression-like behaviors and dysosmia via TLR2-mediated neuroinflammation in mice

BACKGROUND: Depression and dysosmia have been regarded as primary neurological symptoms in COVID-19 patients, the mechanism of which remains unclear. Current studies have demonstrated that the SARS-CoV-2 envelope (E) protein is a pro-inflammatory factor sensed by Toll-like receptor 2 (TLR2), suggest...

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Detalles Bibliográficos
Autores principales: Su, Wenliang, Ju, Jiahang, Gu, Minghui, Wang, Xinrui, Liu, Shaozhuang, Yu, Jiawen, Mu, Dongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166055/
https://www.ncbi.nlm.nih.gov/pubmed/37158916
http://dx.doi.org/10.1186/s12974-023-02786-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166055/
https://www.ncbi.nlm.nih.gov/pubmed/37158916
http://dx.doi.org/10.1186/s12974-023-02786-x

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