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SARS-CoV-2 envelope protein triggers depression-like behaviors and dysosmia via TLR2-mediated neuroinflammation in mice

BACKGROUND: Depression and dysosmia have been regarded as primary neurological symptoms in COVID-19 patients, the mechanism of which remains unclear. Current studies have demonstrated that the SARS-CoV-2 envelope (E) protein is a pro-inflammatory factor sensed by Toll-like receptor 2 (TLR2), suggest...

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Detalles Bibliográficos
Autores principales:	Su, Wenliang, Ju, Jiahang, Gu, Minghui, Wang, Xinrui, Liu, Shaozhuang, Yu, Jiawen, Mu, Dongliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166055/ https://www.ncbi.nlm.nih.gov/pubmed/37158916 http://dx.doi.org/10.1186/s12974-023-02786-x

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