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Synaptojanin1 Modifies Endolysosomal Parameters in Cultured Ventral Midbrain Neurons
The accumulation of α-synuclein (α-syn)-enriched protein aggregates is thought to arise from dysfunction in degradation systems within the brain. Recently, missense mutations of SYNJ1 encoding the SAC1 and 5’-phosphatase domains have been found in families with hereditary early-onset Parkinsonism. P...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Society for Neuroscience
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166127/ https://www.ncbi.nlm.nih.gov/pubmed/37072173 http://dx.doi.org/10.1523/ENEURO.0426-22.2023 |