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The efficacy and the safety of eltrombopag in pediatric patients with severe aplastic anemia: a systematic review

BACKGROUND: Acquired aplastic anemia (AAA) in pediatric patients is a rare disorder characterized by hypocellular bone marrow and pancytopenia. Eltrombopag, an oral thrombopoietin receptor agonist, provides a hematologic improvement in adults with severe aplastic anemia (SAA) refractory to immunosup...

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Detalles Bibliográficos
Autores principales: Marrapodi, Maria Maddalena, Mascolo, Annamaria, Roberti, Domenico, Martino, Martina Di, Rafaniello, Concetta, Riccardi, Consiglia, Rossi, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166202/
https://www.ncbi.nlm.nih.gov/pubmed/37168802
http://dx.doi.org/10.3389/fped.2023.1149718