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New Insights into the Structure and Function of Class B1 GPCRs

G protein–coupled receptors (GPCRs) are the largest family of cell surface receptors. Class B1 GPCRs constitute a subfamily of 15 receptors that characteristically contain large extracellular domains (ECDs) and respond to long polypeptide hormones. Class B1 GPCRs are critical regulators of homeostas...

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Detalles Bibliográficos
Autores principales: Cary, Brian P, Zhang, Xin, Cao, Jianjun, Johnson, Rachel M, Piper, Sarah J, Gerrard, Elliot J, Wootten, Denise, Sexton, Patrick M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166269/
https://www.ncbi.nlm.nih.gov/pubmed/36546772
http://dx.doi.org/10.1210/endrev/bnac033