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A protocol of using PTMiner for quality control and localization of protein modifications identified by open or closed search of tandem mass spectra

In recent years, an open search of tandem mass spectra has greatly promoted the detection of post-translational modifications (PTMs) in shotgun proteomics. However, post-processing of the results from open searches remains an unsatisfactorily resolved problem, which hinders the open search mode from...

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Detalles Bibliográficos
Autores principales: Cheng, Zhiyuan, Song, Ge, Fu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biophysics Reports Editorial Office 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166509/
https://www.ncbi.nlm.nih.gov/pubmed/37287873
http://dx.doi.org/10.52601/bpr.2022.220024