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Epigenomic landscape and 3D genome structure in pediatric high-grade glioma

Pediatric high-grade gliomas (pHGGs), including glioblastoma multiforme (GBM) and diffuse intrinsic pontine glioma (DIPG), are morbid brain tumors. Even with treatment survival is poor, making pHGG the number one cause of cancer death in children. Up to 80% of DIPGs harbor a somatic missense mutatio...

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Detalles Bibliográficos
Autores principales: Wang, Juan, Huang, Tina Yi-Ting, Hou, Ye, Bartom, Elizabeth, Lu, Xinyan, Shilatifard, Ali, Yue, Feng, Saratsis, Amanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166578/
https://www.ncbi.nlm.nih.gov/pubmed/34078608
http://dx.doi.org/10.1126/sciadv.abg4126