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Recombinant Alpha-1-Microglobulin (RMC-035) to Prevent Acute Kidney Injury in Cardiac Surgery Patients: Phase 1b Evaluation of Safety and Pharmacokinetics

INTRODUCTION: Acute kidney injury (AKI) is a common complication in cardiac surgery patients and prevention is needed to improve clinical outcomes. Alpha-1-microglobulin (A1M) is a physiological antioxidant with strong tissue-protective and cell-protective properties that has demonstrated renoprotec...

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Detalles Bibliográficos
Autores principales: Weiss, Raphael, Meersch, Melanie, Wempe, Carola, von Groote, Thilo, Agervald, Tobias, Zarbock, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166741/
https://www.ncbi.nlm.nih.gov/pubmed/37180511
http://dx.doi.org/10.1016/j.ekir.2023.02.1071