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Differential contributions of phosphotransferases CEPT1 and CHPT1 to phosphatidylcholine homeostasis and lipid droplet biogenesis

The cytidine diphosphate-choline (Kennedy) pathway culminates with the synthesis of phosphatidylcholine (PC) and phosphatidylethanolamine (PE) by choline/ethanolamine phosphotransferase 1 (CEPT1) in the endoplasmic reticulum (ER), and PC synthesis by choline phosphotransferase 1 (CHPT1) in the Golgi...

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Detalles Bibliográficos
Autores principales: Dorighello, Gabriel, McPhee, Michael, Halliday, Katie, Dellaire, Graham, Ridgway, Neale D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166788/
https://www.ncbi.nlm.nih.gov/pubmed/36871755
http://dx.doi.org/10.1016/j.jbc.2023.104578