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Landscapes and mechanisms of CD8(+) T cell exhaustion in gastrointestinal cancer

CD8(+) T cells, a cytotoxic T lymphocyte, are a key component of the tumor immune system, but they enter a hyporeactive T cell state in long-term chronic inflammation, and how to rescue this depleted state is a key direction of research. Current studies on CD8(+) T cell exhaustion have found that th...

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Detalles Bibliográficos
Autores principales: Ding, Jia-Tong, Yang, Kang-Ping, Zhou, Hao-Nan, Huang, Ying-Feng, Li, Hui, Zong, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166832/
https://www.ncbi.nlm.nih.gov/pubmed/37180158
http://dx.doi.org/10.3389/fimmu.2023.1149622