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Indicators of increased ER stress and UPR in aged D2-mdx and human dystrophic skeletal muscles

Duchenne muscular dystrophy (DMD) is a progressive muscle disease that results in muscle wasting, wheelchair dependence, and eventual death due to cardiac and respiratory complications. In addition to muscle fragility, dystrophin deficiency also results in multiple secondary dysfunctions, which may...

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Detalles Bibliográficos
Autores principales: Krishna, Swathy, Spaulding, Hannah R., Koltes, James E., Quindry, John C., Valentine, Rudy J., Selsby, Joshua T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166835/
https://www.ncbi.nlm.nih.gov/pubmed/37179835
http://dx.doi.org/10.3389/fphys.2023.1152576