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The m6A methyltransferase METTL16 inhibits the proliferation of pancreatic adenocarcinoma cancer cells via the p21 signaling pathway

BACKGROUND: Many studies have reported that N6-methyladenosine (m6A) modification plays a critical role in the epigenetic regulation of organisms and especially in the pathogenesis of malignant diseases. However, m6A research has mainly focused on methyltransferase activity mediated by METTL3, and f...

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Detalles Bibliográficos
Autores principales: Xie, Fuming, Zheng, Yao, Fu, Wen, Chi, Bojing, Wang, Xianxing, Zhang, Junfeng, Gu, Jianyou, Yin, Jingyang, Zhou, Qiang, Guo, Shixiang, Cai, Lei, Yang, Jiali, Liu, Songsong, Wang, Huaizhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166879/
https://www.ncbi.nlm.nih.gov/pubmed/37182151
http://dx.doi.org/10.3389/fonc.2023.1138238