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AIRE illuminates the feature of medullary thymic epithelial cells in thymic carcinoma

Despite the clear distinction between cortical (cTECs) and medullary thymic epithelial cells (mTECs) in physiology, the cell of origin of thymic carcinomas (TCs) and other thymic epithelial tumors remained enigmatic. We addressed this issue by focusing on AIRE, an mTEC‐specific transcriptional regul...

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Detalles Bibliográficos
Autores principales: Matsumoto, Minoru, Ohmura, Takuya, Hanibuchi, Yuto, Ichimura‐Shimizu, Mayuko, Saijo, Yasuyo, Ogawa, Hirohisa, Miyazawa, Ryuichiro, Morimoto, Junko, Tsuneyama, Koichi, Matsumoto, Mitsuru, Oya, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166898/
https://www.ncbi.nlm.nih.gov/pubmed/36912123
http://dx.doi.org/10.1002/cam4.5777