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The screening of compounds regulating PD‐L1 transcriptional activity in a cell functional high‐throughput manner

Immune checkpoints are protein molecules expressed on the immune cell membrane, which regulate the immune system to kill tumor cells. As an essential immune checkpoint, overexpressed PD‐1 on tumor cells could inhibit T‐cell activation after being bonded to PD‐1. Due to this inhibitory effect, T‐cell...

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Detalles Bibliográficos
Autores principales: Zhang, Lanxin, Li, Hexin, Liu, Jingchao, Sun, Gaoyuan, Tang, Xiaokun, Xu, Siyuan, Zhang, Lili, Zhang, Wei, Ai, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166909/
https://www.ncbi.nlm.nih.gov/pubmed/36965083
http://dx.doi.org/10.1002/cam4.5744