GTN057, a komaroviquinone derivative, induced myeloma cells' death in vivo and inhibited c‐MET tyrosine kinase

OBJECTIVE: Despite the development of newly developed drugs, most multiple myeloma (MM) patients with high‐risk cytogenetic abnormalities such as t(4;14) or del17p relapse at anin early stage of their clinical course. We previously reported that a natural product,komaroviquinone (KQN), isolated from...

Descripción completa

Detalles Bibliográficos
Autores principales: Okayama, Mikio, Fujimori, Kota, Sato, Mariko, Samata, Koichi, Kurita, Koki, Sugiyama, Hiromu, Suto, Yutaka, Iwasaki, Genji, Yamada, Taketo, Kiuchi, Fumiyuki, Ichikawa, Daiju, Matsushita, Maiko, Hirao, Maki, Kunieda, Hisako, Yamazaki, Kohei, Hattori, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
RESEARCH ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166914/
https://www.ncbi.nlm.nih.gov/pubmed/36825580
http://dx.doi.org/10.1002/cam4.5691

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166914/
https://www.ncbi.nlm.nih.gov/pubmed/36825580
http://dx.doi.org/10.1002/cam4.5691

Ejemplares similares