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GTN057, a komaroviquinone derivative, induced myeloma cells' death in vivo and inhibited c‐MET tyrosine kinase
OBJECTIVE: Despite the development of newly developed drugs, most multiple myeloma (MM) patients with high‐risk cytogenetic abnormalities such as t(4;14) or del17p relapse at anin early stage of their clinical course. We previously reported that a natural product,komaroviquinone (KQN), isolated from...
Autores principales: | Okayama, Mikio, Fujimori, Kota, Sato, Mariko, Samata, Koichi, Kurita, Koki, Sugiyama, Hiromu, Suto, Yutaka, Iwasaki, Genji, Yamada, Taketo, Kiuchi, Fumiyuki, Ichikawa, Daiju, Matsushita, Maiko, Hirao, Maki, Kunieda, Hisako, Yamazaki, Kohei, Hattori, Yutaka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166914/ https://www.ncbi.nlm.nih.gov/pubmed/36825580 http://dx.doi.org/10.1002/cam4.5691 |
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