The effects of altered DNA damage repair genes on mutational processes and immune cell infiltration in esophageal squamous cell carcinoma

BACKGROUND: Defects in DNA damage repair (DDR) pathways lead to genomic instability and oncogenesis. DDR deficiency is prevalent in esophageal squamous cell carcinoma (ESCC), but the effects of DDR alterations on mutational processes and tumor immune microenvironment in ECSS remain unclear. METHODS:...

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Detalles Bibliográficos
Autores principales: Yuan, Huangbo, Qing, Tao, Zhu, Sibo, Yang, Xiaorong, Wu, Weicheng, Xu, Kelin, Chen, Hui, Jiang, Yanfeng, Zhu, Chengkai, Yuan, Ziyu, Zhang, Tiejun, Jin, Li, Suo, Chen, Lu, Ming, Chen, Xingdong, Ye, Weimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166979/
https://www.ncbi.nlm.nih.gov/pubmed/36708047
http://dx.doi.org/10.1002/cam4.5663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166979/
https://www.ncbi.nlm.nih.gov/pubmed/36708047
http://dx.doi.org/10.1002/cam4.5663

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