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The effects of altered DNA damage repair genes on mutational processes and immune cell infiltration in esophageal squamous cell carcinoma
BACKGROUND: Defects in DNA damage repair (DDR) pathways lead to genomic instability and oncogenesis. DDR deficiency is prevalent in esophageal squamous cell carcinoma (ESCC), but the effects of DDR alterations on mutational processes and tumor immune microenvironment in ECSS remain unclear. METHODS:...
Autores principales: | Yuan, Huangbo, Qing, Tao, Zhu, Sibo, Yang, Xiaorong, Wu, Weicheng, Xu, Kelin, Chen, Hui, Jiang, Yanfeng, Zhu, Chengkai, Yuan, Ziyu, Zhang, Tiejun, Jin, Li, Suo, Chen, Lu, Ming, Chen, Xingdong, Ye, Weimin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10166979/ https://www.ncbi.nlm.nih.gov/pubmed/36708047 http://dx.doi.org/10.1002/cam4.5663 |
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