Human granzyme B binds Plasmodium falciparum Hsp70-x and mediates antiplasmodial activity in vitro

Cell surface-bound human Hsp70 (hHsp70) sensitises tumour cells to the cytolytic attack of natural killer (NK) cells through the mediation of apoptosis-inducing serine protease, granzyme B (GrB). hHsp70 is thought to recruit NK cells to the immunological synapse via the extracellularly exposed 14 am...

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Detalles Bibliográficos
Autores principales: Ramatsui, Lebogang, Dongola, Tendamudzimu Harmfree, Zininga, Tawanda, Multhoff, Gabriele, Shonhai, Addmore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167072/
https://www.ncbi.nlm.nih.gov/pubmed/37074531
http://dx.doi.org/10.1007/s12192-023-01339-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167072/
https://www.ncbi.nlm.nih.gov/pubmed/37074531
http://dx.doi.org/10.1007/s12192-023-01339-8

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