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Human granzyme B binds Plasmodium falciparum Hsp70-x and mediates antiplasmodial activity in vitro
Cell surface-bound human Hsp70 (hHsp70) sensitises tumour cells to the cytolytic attack of natural killer (NK) cells through the mediation of apoptosis-inducing serine protease, granzyme B (GrB). hHsp70 is thought to recruit NK cells to the immunological synapse via the extracellularly exposed 14 am...
Autores principales: | Ramatsui, Lebogang, Dongola, Tendamudzimu Harmfree, Zininga, Tawanda, Multhoff, Gabriele, Shonhai, Addmore |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167072/ https://www.ncbi.nlm.nih.gov/pubmed/37074531 http://dx.doi.org/10.1007/s12192-023-01339-8 |
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