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Glutathionylation on RNA-binding proteins: a regulator of liquid‒liquid phase separation in the pathogenesis of amyotrophic lateral sclerosis

RNA-binding proteins (RBPs) containing low-sequence complexity domains mediate the formation of cellular condensates and membrane-less organelles with biological functions via liquid‒liquid phase separation (LLPS). However, the abnormal phase transition of these proteins induces the formation of ins...

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Detalles Bibliográficos
Autores principales: Choi, Hyun-Jun, Lee, Ji Young, Kim, Kiyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167235/
https://www.ncbi.nlm.nih.gov/pubmed/37009800
http://dx.doi.org/10.1038/s12276-023-00978-2