Knockdown of mechanosensitive adaptor Hic-5 ameliorates post-traumatic osteoarthritis in rats through repression of MMP-13

Osteoarthritis (OA) is the most common joint disease associated with articular cartilage destruction. Matrix metalloproteinase-13 (MMP-13) has an essential role in OA pathogenesis by degradation of collagen II, a major component of articular cartilage. Hydrogen peroxide-inducible clone-5 (Hic-5; TGF...

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Detalles Bibliográficos
Autores principales: Miyauchi, Aya, Noguchi, Masahito, Lei, Xiao-Feng, Sakaki, Masashi, Kobayashi-Tanabe, Momoko, Haraguchi, Shogo, Miyazaki, Akira, Kim-Kaneyama, Joo-ri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167244/
https://www.ncbi.nlm.nih.gov/pubmed/37156857
http://dx.doi.org/10.1038/s41598-023-34659-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167244/
https://www.ncbi.nlm.nih.gov/pubmed/37156857
http://dx.doi.org/10.1038/s41598-023-34659-x

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