Cargando…
Knockdown of mechanosensitive adaptor Hic-5 ameliorates post-traumatic osteoarthritis in rats through repression of MMP-13
Osteoarthritis (OA) is the most common joint disease associated with articular cartilage destruction. Matrix metalloproteinase-13 (MMP-13) has an essential role in OA pathogenesis by degradation of collagen II, a major component of articular cartilage. Hydrogen peroxide-inducible clone-5 (Hic-5; TGF...
Autores principales: | Miyauchi, Aya, Noguchi, Masahito, Lei, Xiao-Feng, Sakaki, Masashi, Kobayashi-Tanabe, Momoko, Haraguchi, Shogo, Miyazaki, Akira, Kim-Kaneyama, Joo-ri |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167244/ https://www.ncbi.nlm.nih.gov/pubmed/37156857 http://dx.doi.org/10.1038/s41598-023-34659-x |
Ejemplares similares
-
Author Correction: Knockdown of mechanosensitive adaptor Hic-5 ameliorates post-traumatic osteoarthritis in rats through repression of MMP-13
por: Miyauchi, Aya, et al.
Publicado: (2023) -
Alleviation of murine osteoarthritis by deletion of the focal adhesion mechanosensitive adapter, Hic-5
por: Miyauchi, Aya, et al.
Publicado: (2019) -
Hic-5 is required for activation of pancreatic stellate cells and development of pancreatic fibrosis in chronic pancreatitis
por: Gao, Lin, et al.
Publicado: (2020) -
Hic-5, an adaptor-like nuclear receptor coactivator
por: Heitzer, Marjet D., et al.
Publicado: (2006) -
Identification of Hic–5 as a Novel Scaffold for the MKK4/p54 JNK Pathway in the Development of Abdominal Aortic Aneurysms
por: Lei, Xiao‐Feng, et al.
Publicado: (2014)