LncRNA LINC00969 promotes acquired gefitinib resistance by epigenetically suppressing of NLRP3 at transcriptional and posttranscriptional levels to inhibit pyroptosis in lung cancer

Epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) treatment prolongs the survival of lung cancer patients harbouring activating EGFR mutations. However, resistance to EGFR-TKIs is inevitable after long-term treatment. Molecular mechanistic research is of great importance in comba...

Descripción completa

Detalles Bibliográficos
Autores principales: Dai, Jiali, Qu, Tianyu, Yin, Dandan, Cui, Yanan, Zhang, Chen, Zhang, Erbao, Guo, Renhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167249/
https://www.ncbi.nlm.nih.gov/pubmed/37156816
http://dx.doi.org/10.1038/s41419-023-05840-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167249/
https://www.ncbi.nlm.nih.gov/pubmed/37156816
http://dx.doi.org/10.1038/s41419-023-05840-x

Ejemplares similares