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RNA N6-methyladenosine reader IGF2BP3 interacts with MYCN and facilitates neuroblastoma cell proliferation

Neuroblastoma (NB) is a kind of typical life-threatening extracranial tumor in children. N6-methyladenosine (m6A) modification is closely related to multiple cancer pathological processes. Insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3) is a top-ranked prognostic risk gene in NB; howev...

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Detalles Bibliográficos
Autores principales: Zhu, Kai, Gao, Tingting, Wang, Zhiru, Zhang, Liaoran, Tan, Kezhe, Lv, Zhibao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167253/
https://www.ncbi.nlm.nih.gov/pubmed/37156775
http://dx.doi.org/10.1038/s41420-023-01449-3