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FGF21-FGFR1 controls mitochondrial homeostasis in cardiomyocytes by modulating the degradation of OPA1

Fibroblast growth factor 21 (FGF21) is a pleiotropic hormone secreted primarily by the liver and is considered a major regulator of energy homeostasis. Recent research has revealed that FGF21 could play an important role in cardiac pathological remodeling effects and prevention of cardiomyopathy; ho...

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Detalles Bibliográficos
Autores principales: Yan, Bing, Mei, Zhu, Tang, Yaohan, Song, Haixu, Wu, Hanlin, Jing, Quanmin, Zhang, Xiaolin, Yan, Chenghui, Han, Yaling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167257/
https://www.ncbi.nlm.nih.gov/pubmed/37156793
http://dx.doi.org/10.1038/s41419-023-05842-9