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Switching imidazole reactivity by dynamic control of tautomer state in an allosteric foldamer

Molecular biology achieves control over complex reaction networks by means of molecular systems that translate a chemical input (such as ligand binding) into an orthogonal chemical output (such as acylation or phosphorylation). We present an artificial molecular translation device that converts a ch...

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Detalles Bibliográficos
Autores principales: Tilly, David P., Heeb, Jean-Paul, Webb, Simon J., Clayden, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167260/
https://www.ncbi.nlm.nih.gov/pubmed/37156760
http://dx.doi.org/10.1038/s41467-023-38339-2