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BRD4-targeting PROTAC as a unique tool to study biomolecular condensates

Biomolecular condensates play key roles in various biological processes. However, specific condensation modulators are currently lacking. PROTAC is a new technology that can use small molecules to degrade target proteins specifically. PROTAC molecules are expected to regulate biomolecular condensate...

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Detalles Bibliográficos
Autores principales: Shi, Yi, Liao, Yuan, Liu, Qianlong, Ni, Zhihao, Zhang, Zhenzhen, Shi, Minglei, Li, Pilong, Li, Haitao, Rao, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167318/
https://www.ncbi.nlm.nih.gov/pubmed/37156794
http://dx.doi.org/10.1038/s41421-023-00544-0