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BRD4-targeting PROTAC as a unique tool to study biomolecular condensates
Biomolecular condensates play key roles in various biological processes. However, specific condensation modulators are currently lacking. PROTAC is a new technology that can use small molecules to degrade target proteins specifically. PROTAC molecules are expected to regulate biomolecular condensate...
Autores principales: | Shi, Yi, Liao, Yuan, Liu, Qianlong, Ni, Zhihao, Zhang, Zhenzhen, Shi, Minglei, Li, Pilong, Li, Haitao, Rao, Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167318/ https://www.ncbi.nlm.nih.gov/pubmed/37156794 http://dx.doi.org/10.1038/s41421-023-00544-0 |
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