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Plasmodium falciparum has evolved multiple mechanisms to hijack human immunoglobulin M

Plasmodium falciparum causes the most severe malaria in humans. Immunoglobulin M (IgM) serves as the first line of humoral defense against infection and potently activates the complement pathway to facilitate P. falciparum clearance. A number of P. falciparum proteins bind IgM, leading to immune eva...

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Detalles Bibliográficos
Autores principales: Ji, Chenggong, Shen, Hao, Su, Chen, Li, Yaxin, Chen, Shihua, Sharp, Thomas H., Xiao, Junyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167334/
https://www.ncbi.nlm.nih.gov/pubmed/37156765
http://dx.doi.org/10.1038/s41467-023-38320-z