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Plasmodium falciparum has evolved multiple mechanisms to hijack human immunoglobulin M
Plasmodium falciparum causes the most severe malaria in humans. Immunoglobulin M (IgM) serves as the first line of humoral defense against infection and potently activates the complement pathway to facilitate P. falciparum clearance. A number of P. falciparum proteins bind IgM, leading to immune eva...
Autores principales: | Ji, Chenggong, Shen, Hao, Su, Chen, Li, Yaxin, Chen, Shihua, Sharp, Thomas H., Xiao, Junyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167334/ https://www.ncbi.nlm.nih.gov/pubmed/37156765 http://dx.doi.org/10.1038/s41467-023-38320-z |
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