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Altered acylcarnitine metabolism and inflexible mitochondrial fuel utilization characterize the loss of neonatal myocardial regeneration capacity

Myocardial regeneration capacity declines during the first week after birth, and this decline is linked to adaptation to oxidative metabolism. Utilizing this regenerative window, we characterized the metabolic changes in myocardial injury in 1-day-old regeneration-competent and 7-day-old regeneratio...

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Detalles Bibliográficos
Autores principales: Kankuri, E., Finckenberg, P., Leinonen, J., Tarkia, M., Björk, S., Purhonen, J., Kallijärvi, J., Kankainen, M., Soliymani, R., Lalowski, M., Mervaala, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167339/
https://www.ncbi.nlm.nih.gov/pubmed/37009793
http://dx.doi.org/10.1038/s12276-023-00967-5