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Targeting glutamine metabolism as a therapeutic strategy for cancer

Proliferating cancer cells rely largely on glutamine for survival and proliferation. Glutamine serves as a carbon source for the synthesis of lipids and metabolites via the TCA cycle, as well as a source of nitrogen for amino acid and nucleotide synthesis. To date, many studies have explored the rol...

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Detalles Bibliográficos
Autores principales: Jin, Jonghwa, Byun, Jun-Kyu, Choi, Yeon-Kyung, Park, Keun-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167356/
https://www.ncbi.nlm.nih.gov/pubmed/37009798
http://dx.doi.org/10.1038/s12276-023-00971-9