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GATA4-activated lncRNA MALAT1 promotes osteogenic differentiation through inhibiting NEDD4-mediated RUNX1 degradation

Postmenopausal osteoporosis (PMOP) brings a lot of inconvenience to patients and serious economic burden to society. The osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) plays vital role in the process of PMOP treatment. However, the functional mechanism remains unclear. In t...

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Detalles Bibliográficos
Autores principales: Huang, Xianzhe, Jie, Shuo, Li, Wenzhao, Liu, Chan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167365/
https://www.ncbi.nlm.nih.gov/pubmed/37156809
http://dx.doi.org/10.1038/s41420-023-01422-0