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Cdyl2-60aa encoded by CircCDYL2 accelerates cardiomyocyte death by blocking APAF1 ubiquitination in rats

The loss of cardiomyocytes (CMs) after myocardial infarction (MI) is widely acknowledged to initiate the development of heart failure (HF). Herein, we found that circCDYL2 (583 nt) derived from chromodomain Y-like 2 (Cdyl2) is significantly upregulated in vitro (oxygen-glucose deprivation (OGD)-trea...

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Detalles Bibliográficos
Autores principales: Deng, Yunfei, Zeng, Xiaochen, Lv, Yifei, Qian, Zhiyuan, Guo, Peijie, Liu, Yi, Chen, Shaoliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167378/
https://www.ncbi.nlm.nih.gov/pubmed/37009805
http://dx.doi.org/10.1038/s12276-023-00983-5