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A methylation clock model of mild SARS‐CoV‐2 infection provides insight into immune dysregulation

DNA methylation comprises a cumulative record of lifetime exposures superimposed on genetically determined markers. Little is known about methylation dynamics in humans following an acute perturbation, such as infection. We characterized the temporal trajectory of blood epigenetic remodeling in 133...

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Detalles Bibliográficos
Autores principales: Mao, Weiguang, Miller, Clare M, Nair, Venugopalan D, Ge, Yongchao, Amper, Mary Anne S, Cappuccio, Antonio, George, Mary‐Catherine, Goforth, Carl W, Guevara, Kristy, Marjanovic, Nada, Nudelman, German, Pincas, Hanna, Ramos, Irene, Sealfon, Rachel S G, Soares‐Schanoski, Alessandra, Vangeti, Sindhu, Vasoya, Mital, Weir, Dawn L, Zaslavsky, Elena, Kim‐Schulze, Seunghee, Gnjatic, Sacha, Merad, Miriam, Letizia, Andrew G, Troyanskaya, Olga G, Sealfon, Stuart C, Chikina, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167476/
https://www.ncbi.nlm.nih.gov/pubmed/36919946
http://dx.doi.org/10.15252/msb.202211361