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Molecular mechanisms protecting centromeres from self-sabotage and implications for cancer therapy
Centromeres play a crucial role in DNA segregation by mediating the cohesion and separation of sister chromatids during cell division. Centromere dysfunction, breakage or compromised centromeric integrity can generate aneuploidies and chromosomal instability, which are cellular features associated w...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167631/ https://www.ncbi.nlm.nih.gov/pubmed/37180029 http://dx.doi.org/10.1093/narcan/zcad019 |