Reaction Mechanism of Glycoside Hydrolase Family 116 Utilizes Perpendicular Protonation

[Image: see text] Retaining glycoside hydrolases use acid/base catalysis with an enzymatic acid/base protonating the glycosidic bond oxygen to facilitate leaving-group departure alongside attack by a catalytic nucleophile to form a covalent intermediate. Generally, this acid/base protonates the oxyg...

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Detalles Bibliográficos
Autores principales: Pengthaisong, Salila, Piniello, Beatriz, Davies, Gideon J., Rovira, Carme, Ketudat Cairns, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167657/
https://www.ncbi.nlm.nih.gov/pubmed/37180965
http://dx.doi.org/10.1021/acscatal.3c00620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167657/
https://www.ncbi.nlm.nih.gov/pubmed/37180965
http://dx.doi.org/10.1021/acscatal.3c00620

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