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FLEXR: automated multi-conformer model building using electron-density map sampling
Protein conformational dynamics that may inform biology often lie dormant in high-resolution electron-density maps. While an estimated ∼18% of side chains in high-resolution models contain alternative conformations, these are underrepresented in current PDB models due to difficulties in manually det...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167668/ https://www.ncbi.nlm.nih.gov/pubmed/37071395 http://dx.doi.org/10.1107/S2059798323002498 |