Cargando…
Structural insight into an anti-BRIL Fab as a G-protein-coupled receptor crystallization chaperone
Structure determination of G-protein-coupled receptors (GPCRs) is key for the successful development of efficient drugs targeting GPCRs. BRIL is a thermostabilized apocytochrome b (562) (with M7W/H102I/R106L mutations) from Escherichia coli and is often used as a GPCR fusion protein for expression a...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167669/ https://www.ncbi.nlm.nih.gov/pubmed/37098908 http://dx.doi.org/10.1107/S205979832300311X |