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Continuous-Flow Synthesis of Δ(9)-Tetrahydrocannabinol and Δ(8)-Tetrahydrocannabinol from Cannabidiol
[Image: see text] A challenging step in the preparation of tetrahydrocannabinol analogs is an acid-catalyzed intramolecular cyclization of the cannabidiol precursor. This step typically affords a mixture of products, which requires extensive purification to obtain any pure products. We report the de...
Autores principales: | Bassetti, Benedetta, Hone, Christopher A., Kappe, C. Oliver |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167683/ https://www.ncbi.nlm.nih.gov/pubmed/37014222 http://dx.doi.org/10.1021/acs.joc.3c00300 |
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