Stereocontrolled Access to Quaternary Centers by Birch Reduction/Alkylation of Chiral Esters of Salicylic Acids

[Image: see text] 8-Phenylmenthol esters of salicylic acid derivatives undergo efficient Birch reduction and in situ diastereoselective alkylations to afford methoxycyclohexadienes bearing new quaternary stereogenic centers. The use of an ester-based auxiliary is a designed improvement over the use...

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Detalles Bibliográficos
Autores principales: Kozlowski, Ryan A., Nguyen, Hanh T., Lehman, Michael E., Vanderwal, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167686/
https://www.ncbi.nlm.nih.gov/pubmed/37040358
http://dx.doi.org/10.1021/acs.joc.3c00306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167686/
https://www.ncbi.nlm.nih.gov/pubmed/37040358
http://dx.doi.org/10.1021/acs.joc.3c00306

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