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The antiproliferative potential and mechanism of action of metformin in MCF-7 cells

AIM: The current study aimed to investigate the potential antiproliferative activity of metformin, the effective concentration range, and the mechanism of action. MATERIALS & METHODS: Human breast cancer cells, MCF-7 were treated with a serial dilution of metformin (10–150 μM) for 24 and 48 h. P...

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Detalles Bibliográficos
Autores principales: Bekezhankyzy, Zhibek, Nurzhan, Sholpan, Berdigaliyev, Nurken, Sergazy, Shynggys, Maulenkul, Tilektes, Aljofan, Mohamad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167719/
https://www.ncbi.nlm.nih.gov/pubmed/37180606
http://dx.doi.org/10.2144/fsoa-2022-0080