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Exploring the therapeutic mechanisms of Gleditsiae Spina acting on pancreatic cancer via network pharmacology, molecular docking and molecular dynamics simulation

Pancreatic cancer is one of the most aggressive tumors and also has a low survival rate. The dried spines of Gleditsia sinensis Lam are known as “Gleditsiae Spina” and they mostly contain flavonoids, phenolic acids, terpenoids, steroids, and other chemical components. In this study, the potential ac...

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Detalles Bibliográficos
Autores principales: Duan, Hongtao, Zhang, Rui, Yuan, Lu, Liu, Yiyuan, Asikaer, Aiminuer, Liu, Yang, Shen, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167735/
https://www.ncbi.nlm.nih.gov/pubmed/37181515
http://dx.doi.org/10.1039/d3ra01761c