Impact of the Recognition Part of Dipeptidyl Nitroalkene Compounds on the Inhibition Mechanism of Cysteine Proteases Cruzain and Cathepsin L

[Image: see text] Cysteine proteases (CPs) are an important class of enzymes, many of which are responsible for several human diseases. For instance, cruzain of protozoan parasite Trypanosoma cruzi is responsible for the Chagas disease, while the role of human cathepsin L is associated with some can...

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Detalles Bibliográficos
Autores principales: Arafet, Kemel, Royo, Santiago, Schirmeister, Tanja, Barthels, Fabian, González, Florenci V., Moliner, Vicent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167892/
https://www.ncbi.nlm.nih.gov/pubmed/37180968
http://dx.doi.org/10.1021/acscatal.3c01035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10167892/
https://www.ncbi.nlm.nih.gov/pubmed/37180968
http://dx.doi.org/10.1021/acscatal.3c01035

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