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UBE2T Promotes Temozolomide Resistance of Glioblastoma Through Regulating the Wnt/β-Catenin Signaling Pathway

PURPOSE: Patients with glioblastoma (GBM) have poor prognosis and limited therapeutic options, largely because of chemoresistance to temozolomide (TMZ) treatment. Ubiquitin conjugating enzyme E2 T (UBE2T) plays a key role in regulating the malignancy of various tumors, including GBM; however, its ro...

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Detalles Bibliográficos
Autores principales: Wang, Yang, Gao, Ge, Wei, Xiangpin, Zhang, Yang, Yu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168001/
https://www.ncbi.nlm.nih.gov/pubmed/37181827
http://dx.doi.org/10.2147/DDDT.S405450