Microglial CD11b Knockout Contributes to Axonal Debris Clearance and Axonal Degradation Attenuation via IGF-1 After Acute Optic Nerve Injury

PURPOSE: Microglial clearance of axonal debris is an essential response for management of traumatic optic neuropathy. Inadequate removal of axonal debris leads to increased inflammation and axonal degeneration after traumatic optic neuropathy. The present study investigated the role of CD11b (Itgam)...

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Detalles Bibliográficos
Autores principales: Zhou, Jiaxing, Lin, Sen, Hu, Qiumei, Li, Xue, Chen, Xi, Luo, Linlin, Ye, Shiyang, Liu, Wei, Ye, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Retina
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168008/
https://www.ncbi.nlm.nih.gov/pubmed/37145604
http://dx.doi.org/10.1167/iovs.64.5.7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168008/
https://www.ncbi.nlm.nih.gov/pubmed/37145604
http://dx.doi.org/10.1167/iovs.64.5.7

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