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Population Pharmacokinetic Model and Dosing Simulation of Meropenem Using Measured Creatinine Clearance for Patients with Sepsis

Creatinine clearance (CCr) and pharmacokinetic parameters are markedly affected by pathophysiological changes in patients with sepsis. However, only a few reports have assessed renal function in patients with sepsis using the measured CCr. Furthermore, the administration regimen has not been suffici...

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Detalles Bibliográficos
Autores principales: Fukumoto, Shiori, Ohbayashi, Masayuki, Okada, Akira, Kohyama, Noriko, Tamatsukuri, Tatsuro, Inoue, Hideki, Kato, Akihito, Kotani, Toru, Sagara, Hironori, Dohi, Kenji, Kogo, Mari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Therapeutic Drug Monitoring 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168112/
https://www.ncbi.nlm.nih.gov/pubmed/36253888
http://dx.doi.org/10.1097/FTD.0000000000001040