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Cruciferous vegetable-derived indole-3-carbinol prevents coronavirus cell egression mechanisms in tracheal and intestinal 3D in vitro models.

The potential antiviral effects of indole-3-carbinol (I3C), a phytochemical found in Cruciferous vegetables, were investigated. Fibroblasts and epithelial cells were co-cultured on Alvetex® scaffolds, to obtain ad hoc 3D in vitro platforms able to mimic the trachea and intestinal mucosae, which repr...

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Detalles Bibliográficos
Autores principales: Pennarossa, Georgia, Arcuri, Sharon, Pasquariello, Rolando, Gandolfi, Fulvio, Maranesi, Margherita, Brevini, Tiziana A.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168192/
https://www.ncbi.nlm.nih.gov/pubmed/37169138
http://dx.doi.org/10.1016/j.phytochem.2023.113713