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Cruciferous vegetable-derived indole-3-carbinol prevents coronavirus cell egression mechanisms in tracheal and intestinal 3D in vitro models.
The potential antiviral effects of indole-3-carbinol (I3C), a phytochemical found in Cruciferous vegetables, were investigated. Fibroblasts and epithelial cells were co-cultured on Alvetex® scaffolds, to obtain ad hoc 3D in vitro platforms able to mimic the trachea and intestinal mucosae, which repr...
Autores principales: | Pennarossa, Georgia, Arcuri, Sharon, Pasquariello, Rolando, Gandolfi, Fulvio, Maranesi, Margherita, Brevini, Tiziana A.L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168192/ https://www.ncbi.nlm.nih.gov/pubmed/37169138 http://dx.doi.org/10.1016/j.phytochem.2023.113713 |
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